Written by Nick Enright and director George Miller, Lorenzo’s Oil has a limited release before going wide in January. Nick Nolte and Susan Sarandon star as Augusto and Michaela Odone, the real life academic couple whose world is overturned when their seven year-old son is stricken with ALD, a rare, incurable brain disease. Defying the received wisdom of an indifferent medical community, the couple's selfless, unprecedented, seven year search for a cure culminates with the discovery of an oil which effectively arrests the disease's mestastasis. A heartbreaking, unsentimental human drama shot with the precision of a gripping thriller.