Written by Harry Kleiner, based on a treatment by Otto Klement, Jerome Lewis Bixby and David Duncan, and directed by Richard Fleischer, Fantastic Voyage premieres in Los Angeles. When an assassination attempt renders a just defected Russian physicist comatose by a brain tumour that can only be operated on from the inside, a team of American scientists board a nuclear submarine which is then miniturised to the size of a microbe and injected into the physicist's bloodstream. Given only 60 minutes to reach the brain and dissolve the tumour before they and the sub revert back to their original sizes, the crew’s perilous voyage through fields of aggressive white blood cells and stormy rapids inside the heart is further endangered by an onboard saboteur. One of the most inventive, entertaining Cold War-themed sci-fi thrillers of the 1960s, featuring Stephen Boyd, Raquel Welch, Donald Pleasance and Edmond O’Brien.